Texas Sens. John Cornyn and Ted Cruz also voted against the nomination.
The president said he was pleased with the strong support represented by the vote.
“I am pleased that the Senate has confirmed John Kerry as our next Secretary of State with overwhelming bipartisan support,” President Barack Obama said. “From his decorated service in Vietnam to his decades in the Senate as a champion of American global leadership, John’s distinguished career has prepared him to guide American diplomacy in the years ahead.”
Inhofe maintains that despite his friendship with Kerry, he believes the Massachusetts senator has been “on the wrong side of history.”