The Norman Transcript

Headlines

November 20, 2012

Brain injuriesResearch suffers a setback

CHICAGO — The hunt for brain injury treatments has suffered a big disappointment in a major study that found zero benefits from a supplement that the U.S. military had hoped would help wounded troops.

The supplement is marketed as a memory booster online and in over-the-counter powders and drinks. It is also widely used by doctors in dozens of countries to treat traumatic brain injuries and strokes, although evidence on whether it works has been mixed.

U.S. scientists had high hopes that in large doses it would help speed recovery in patients with brain injuries from car crashes, falls, sports accidents and other causes. But in the most rigorous test yet, citicoline worked no better than dummy treatments at reducing forgetfulness, attention problems, difficulty concentrating and other symptoms.

“We very much were disappointed,” said Dr. Ross Zafonte, the lead author and a traumatic brain injury expert at Harvard Medical School. “We took a therapy that is utilized worldwide and we found that at least its present use should be called into question.”

The study involved 1,213 patients aged 18 and older hospitalized at eight U.S. trauma centers. They had mild to severe traumatic brain injuries — blows to the head resulting in symptoms ranging from dizziness to loss of consciousness and with complications including brain bleeding or other damage.

Half of the patients received citicoline — also known as CDP choline — in pills or in liquid within 24 hours of being injured. The dose of 2,000 milligrams was much higher than used in over-the-counter products and it was given daily for three months. The rest got a dummy treatment.

Most patients improved on measures of memory, learning and other mental functions, but those on the supplement fared no better than those given a placebo.

For local news and more, subscribe to The Norman Transcript Smart Edition, or our print edition.

1
Text Only | Photo Reprints
Headlines
  • Human Rights Artist, activist-in-residence uses art to enlighten society

    La Puerta del Mileno, the Millennium Door, attempts to beckon travelers into the city walls of Ciudad Juarez, but the steel beams are abruptly interrupted as they reach for the sky by the eye of a child who sees the underlying message: the ...

    April 17, 2014 1 Photo

  • Oklahoma Water Resources Board grants Norman low-interest loan for facility upgrade

    Norman has been authorized for a $50.3 million loan from the Oklahoma Water Resources Board to fund Phase 2 of the Norman Water Reclamation Facility upgrade. “It’s the single largest loan OWRB has made,” Norman Mayor Cindy Rosenthal said. ...

    April 17, 2014

  • Oklahoma’s superintendent attracts opponents

    OKLAHOMA CITY — The field of candidates running for state school superintendent is unusually large — a sign of broad interest in what observers say is sure to be a referendum on the incumbent, Dr. Janet Barresi....

    April 17, 2014

  • Women leaders announced

    The Norman Chamber announced the nominees for the 2014 Women’s Leadership Award, which honors female leaders who actively inspire other women to achieve their full potential.  Past recipients of this honor, formerly known as the ATHENA ...

    April 17, 2014

  • Organizers confident of safe race

    BOSTON — The arrest of a man with a rice cooker in his backpack near the Boston Marathon finish line led police to step up patrols Wednesday, while organizers sought to assure the city and runners of a safe race next week....

    April 17, 2014

  • Ducks Unlimited night set

    Cleveland County’s chapter of Ducks Unlimited will host its annual “Sportsman Night” at 6 p.m. April 25 at the Optimist Club Gym in Norman....

    April 17, 2014

  • Record number of NPS students selected for Duke program

    A record number of Norman Public Schools seventh-graders have been selected for Duke University’s Talent Identification Search for State and National Recognition. Fifty-one students were identified via a competitive testing process for ...

    April 17, 2014

  • Fed says no to business help

    LEXINGTON — The federal government has turned down the state’s request for an economic injury declaration from the U.S. Small Business Administration following the Jan. 31 closure of the Lexington-Purcell bridge over the Canadian River....

    April 17, 2014

  • History group to host local book signing event

    Mae Davenport Cox will sign copies of “Red Dirt, River and Rails: Early-Day Settlers to Southern Cleveland County” from 10 a.m. to 3 p.m. Saturday at the Lexington Senior Citizen Center during ‘89er Day festivities....

    April 17, 2014

  • OU Staff Week to include daily activities

    The University of Oklahoma Norman campus Staff Week, set April 21-25, will feature many activities. The theme is “OU Staff: The Real Superheroes.” Donations of canned food for Food and Shelter may be brought to all activities except the ...

    April 17, 2014