The Norman Transcript

Headlines

October 25, 2012

Study: Aspirin may help treat some colon cancers

NEW YORK — Aspirin has shown remarkable promise in treating colon cancer in people with mutations in a gene that’s thought to play a role in the disease.

Among patients with the mutations, those who regularly took aspirin lived longer than those who didn’t, a major study found. Five years after their cancers were diagnosed, 97 percent of the aspirin users were still alive versus 74 percent of those not taking the drug.

Aspirin seemed to make no difference in patients who did not have the mutations.

This sort of study can’t prove that aspirin caused the better survival, and doctors say more research must confirm the findings before aspirin can be recommended more widely. The study wasn’t designed to test aspirin; people were taking it on their own for various reasons.

Still, the results suggest that this simple medicine might be the cheapest gene-targeting therapy ever found for cancer. About one-sixth of all colon cancer patients have the mutated gene and might be helped by aspirin.

“It’s exciting to think that something that’s already in the medicine cabinet may really have an important effect” beyond relieving pain and helping to prevent heart attacks, said Dr. Andrew Chan of Massachusetts General Hospital. He and others from Harvard Medical School led the study.

Cancers of the colon or rectum are a leading cause of cancer deaths worldwide. More than 140,000 new cases and 51,000 deaths from them are expected this year in the United States.

Several studies suggest that aspirin may help fight cancer, especially colorectal tumors. It is often recommended for people who have colon cancer and others at high risk of developing it. But it’s not advised for wider use, or for cancer prevention, because it can cause serious bleeding in the stomach and gut.

What has been lacking, doctors say, is a good way to tell which people might benefit the most, so aspirin’s risks would be justified. Chan’s study suggests a way to do that.

Text Only | Photo Reprints
Headlines
  • Baker home 3 Moore resident lands in new home 14 months after tornado

    She crawled from the rubble of what used to be her home. The neighborhood was destroyed. It was the afternoon of May 20, 2013, and Jamie Baker was homeless....

    July 30, 2014 1 Photo

  • Additional details come to light in Campus Corner incident involving Sooner recruit

    The 911 call from Pickleman’s Gourmet Cafe early Friday morning brought forth more details from the incident that has Oklahoma running back Joe Mixon under investigation for an alleged assault....

    July 30, 2014

  • Police rule out homicide in Norman woman’s death

    Norman Police Capt. Todd Gibson said Tuesday they have eliminated the theory of homicide after a Norman woman was found dead in her home Monday afternoon. “We’re moving in a different direction with the investigation,” Gibson said. “It’s ...

    July 30, 2014

  • Voter registration deadline is Friday

    Friday is the last day to apply for voter registration to be eligible to vote in the Aug. 26 Runoff Primary Election. Races include federal, state and county offices, but for Cleveland County voters, the field is limited....

    July 30, 2014

  • Norman High student argues his way to the top

    Knowing the ins and outs of an argument that involves complex research is the type of skill one expects a high paid attorney to have not a high school student. Yet debate competitor Nicky Halterman has been arguing his way to the top of ...

    July 30, 2014

  • Senate approves new VA secretary

    WASHINGTON — The Senate on Tuesday unanimously confirmed former Procter & Gamble CEO Robert McDonald as the new Veterans Affairs secretary, with a mission to overhaul an agency beleaguered by long veterans’ waits for health care and VA ...

    July 30, 2014

  • Tampering accusations surface in OKC bombing case

    SALT LAKE CITY — A Utah lawyer suing the FBI over his public records request for surveillance videos from the 1995 Oklahoma City bombing said Tuesday that one of his witnesses backed out after being visited by government officials last ...

    July 30, 2014

  • Shelter construction ongoing; residents voice concerns

    A regular quarterly meeting of the Animal Shelter Oversight Board prompted Norman residents to speak up about more than just a photo release issue Monday night involving Friends of the Animals of Norman volunteers and the city of Norman. ...

    July 30, 2014

  • Senate passes highway bill, sends it to House

    WASHINGTON — The Senate on Tuesday voted to change the funding and timing of a House bill to keep federal highway funds flowing to states in an effort to force Congress to come to grips with chronic funding problems that have plagued ...

    July 30, 2014

  • Police log

    Police responded to the following incidents Monday: · 8:20 a.m. larceny report, 2000 block of West Lindsey Street · 9:04 a.m. stolen vehicle, 3400 block of Bart Conner Drive · 9:11 a.m. larceny report, 1200 block of Ed ...

    July 30, 2014