ST. LOUIS —
Off and running:Kaepernick hasn’t hurt defenses much with his legs thus far, and the Rams will do their best to keep it that way by making him pay for any forays.
Neither team has generated much on the ground, with Frank Gore getting just 11 carries last week and totaling 142 yards on the season. No Rams players are over 100 yards.
Penalty problems: San Francisco followed 12 penalties for 121 yards in a 29-3 rout at Seattle with six more for 48 yards in Sunday’s 27-7 loss to the Colts, taking the 49ers’ flag total to 29.
San Francisco’s defense gave Indianapolis five first downs by penalty, including on the first two snaps of the game.
“There were first downs by penalty. And, again, in a game that we were really a touchdown away at 13-7, up until seven minutes left in the fourth quarter, and there was a key drive there,” Harbaugh said.