Minnesota transfer and Rams big man Colton Iverson outrebounded Missouri by himself through 27 minutes and finished with 13 boards.
First-year Rams coach Larry Eustachy earned the victory with his fourth tournament team, but the road gets tougher as they advance to face top-seeded Louisville in Saturday’s third-round Midwest Regional game at Rupp Arena.
Phil Pressey’s 20 points led the Tigers (23-11).
VCU 88, Akron 42: Troy Daniels had 23 points, Juvonte Reddic scored 21 and VCU routed Akron 88-42 on Thursday night in the most lopsided victory by a fifth-seeded team over a No. 12 in NCAA tournament history.
The previous mark was set by Wyoming in a 35-point win over Howard in 1981 and matched by Tennessee against Long Beach State in 2007, according to STATS.
The Rams (27-8) will play fourth-seeded Michigan on Saturday for a spot in the round of 16.
Akron (26-7) was seriously short-handed, and it showed.
Marquette 59, Davidson 58: Vander Blue’s layup with one second left capped Marquette’s rally from a nine-point deficit and gave the third-seeded Golden Eagles a 59-58 victory over Davidson Thursday in the NCAA tournament.
Blue and Jamil Wilson made consecutive 3-pointers to bring Marquette within 58-57 with 11 seconds left. The Golden Eagles then caught a huge break when De’Mon Brooks’ long inbounds pass went out of bounds at midcourt with 5.5 seconds left, providing another opportunity.
Jake Cohen’s 20 points led Davidson (26-8), who seemed in control leading 49-40 with 6 1/2 minutes left.
Butler 68, Bucknell 56: Andrew Smith had a double-double including a career-high 16 rebounds, Roosevelt Jones added 14 points and Butler made its free throws down the stretch to hold off upset-minded Bucknell.
After trailing for most of the game, 11th-seeded Bucknell got back into it with a 19-2 second-half run. But after Joe Willman’s jumper cut Butler’s lead to 43-42 with 6:56 left, the Bison (28-6) went almost five minutes without scoring. Butler went 18-of-20 at the line in the last 4:43.