Oklahoma and Baylor were awarded a primetime kickoff Nov. 16.
The game will kick off at 6:30 p.m. at McLane Stadium in Waco with coverage on ABC.
The Sooners (7-1, 4-1 Big 12) could face an undefeated Baylor team; the 11th-ranked Bears are 8-0 and 5-0 in conference play going into Saturday's game at TCU.
OU has played five consecutive 11 a.m. kicks, but will now receive two nighttime starts. Saturday's game in Norman against Iowa State will start at 7 p.m.